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DeCS
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Descriptor English:
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Protein Kinase C
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Descriptor Spanish:
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Proteína Quinasa C
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Descriptor Portuguese:
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Proteína Quinase C
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Synonyms English:
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Calcium-Activated Phospholipid-Dependent Kinase
Calcium Phospholipid-Dependent Protein Kinase
PKC Serine-Threonine Kinase
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Tree Number:
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D08.811.913.696.620.682.700.725
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Definition English:
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An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters. |
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History Note English:
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86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93
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Allowable Qualifiers English:
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Record Number:
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19587
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Unique Identifier:
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D011493
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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